Trace Amines (TAs) & Trace Amine-Associated Receptors (TAARs)
TAs are endogenous chemical messengers and metabolites of amino acids1-3
- Structurally similar to the monoamine neurotransmitters, dopamine, norepinephrine, and serotonin1-3
- Expressed at levels at least 100-fold lower than corresponding neurotransmitters2
In 2001, TAs were found to selectively activate a family of receptors called TAARs1
- Predominantly intracellular location2
- Members of the G-protein coupled receptor family
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Therapeutic Potential for TAAR1 Agonists: Preclinical Evidence1,3,4
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​The safety and efficacy of TAAR1 agents have not been reviewed or approved by any drug/medicine regulatory agency and have no indication at this time. For use with medical professionals only.